OUR TECHNOLOGY
We have developed a ultra low cost, compact, versatile biosensing platform for rapid sample-to-read detection of biological targets under 30 minutes.
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Simple printed circuit boards (PCBs) are functionalized with our proprietary modular chemistries, enabling direct detection in biofluids with no upfront sample processing or on-board microfluidics.
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Our platform provides multiplexed, quantitative detection and is unaffected by complex biological fluid matrices including unprocessed capillary blood.
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This platform is ideal for rapid at-home testing.
CURRENT PROGRAMS
HEART FAILURE
Our platform can be used at home to frequently and precisely monitor cardiac biomarkers in the patients' blood which are indicators of heart failure progression, including NT-proBNP, CRP, and Cardiac Troponin I. This enables clinicians to up-titrate medications and prevent complications and hospital readmissions.
INFECTIOUS DISEASE
Our platform can be used for rapid detection of infectious diseases such as COVID-19 by measuring the level of SARS-CoV-2 virus in saliva.
CHRONIC INFLAMATORY SKIN CONDITIONS
Our platform can be used at home or to detect and quantify skin pathogen concentrations, to inform precise treatment.
LITERATURE
Learn about Arma's platform sensing technology in top peer-reviewed literature
CARDIOVASCULAR
Agnewandte Chemie, March 9, 2023
Monitoring Cardiac Biomarkers with Aptamer-Based Molecular Pendulum Sensors
Alam Mahmud, Dingran Chang, Jagotamoy Das, Surath Gomis, Farid Foroutan, Jenise B. Chen, Laxman Pandey, Connor D. Flynn, Hanie Yousefi, Armin Geraili, Heather J. Ross, Edward H. Sargent, Shana Olwyn Kelley
PLATFORM TECHNOLOGY
American Chemical Society, September 29, 2022
Capillary-Assisted Molecular Pendulum Bioanalysis
Hossein Zargartalebi, Hanie Yousefi, Connor D. Flynn, Surath Gomis, Jagotamoy Das, Tiana L. Young, Emily Chien, Samira Mubareka, Allison McGeer, Hansen Wang, Edward H. Sargent, Amir Sanati Nezhad, and Shana O. Kelley
CARDIOVASCULAR
Circulation, November 8, 2021
Precision Quantification of Cardiac Biomarkers Using Reagent-Free Electrochemical Aptasensors
Alam Mahmud, Jagotamoy Das, Dingran Chang, Surath Gomis, Jenise Chen, Hanie Yousefi, Edward H Sargent & Shana O Kelley
PLATFORM TECHNOLOGY
Nature Chemistry, March 8, 2021
Reagentless biomolecular analysis using a molecular pendulum
Jagotamoy Das, Surath Gomis, Jenise B. Chen, Hanie Yousefi, Sharif Ahmed, Alam Mahmud, Wendi Zhou, Edward H. Sargent, & Shana O. Kelley
CARDIOVASCULAR
Electrochemical Society, February 1, 2021
Monitoring of Cardiac Disease with Reagent-free Molecular Pendulum Aptasensors
Alam Mahmud, Jagotamoy Das, Dingran Chang, Surath Gomis, Jenise Chen, Hanie Yousefi, Edward Sargent and Shana Kelley
INFECTIOUS DISEASE
American Chemical Society, January 22, 2021
Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing
Hanie Yousefi, Alam Mahmud, Dingran Chang, Jagotamoy Das, Surath Gomis, Jenise B. Chen, Hansen Wang, Terek Been, Lily Yip, Eric Coomes, Zhijie Li, Samira Mubareka, Allison McGeer, Natasha Christie, Scott Gray-Owen, Alan Cochrane, James M. Rini, Edward H. Sargent, & Shana O. Kelley